(S)-Tenofovir

CAS: 147127-19-3

Ref. TR-T018480

Product Information

• Name: (S)-Tenofovir
• Synonyms: Phosphonic acid, P-[[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, Phosphonic acid, [[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI), Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, (S)-, P-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid, (S)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonicacid, (S)-9-(2-Phosphonomethoxypropyl)adenine, (S)-PMPA
• Brand: TRC
• Description: Applications (S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts.References Balzarini, J. et al: Biochem. Biophys. Res. Comm., 219, 337 (1996); Balzarini, J. et al.: Antimicrob. Agents. Ch., 37, 332 (1993); Thormar, H. et al.: Antimicorb. Agents. Ch., 37, 2540 (1993)

Chemical properties

• Molecular weight: 287.21
• Formula: C₉H₁₄N₅O₄P
• Color/Form: Neat
• InChI: InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1
• InChI key: InChIKey=SGOIRFVFHAKUTI-LURJTMIESA-N
• SMILES: C[C@@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O