Tenofovir Disoproxil-d6 Fumarate

CAS: 202138-50-9

Ref. TR-T018507

Product Information

• Name: Tenofovir Disoproxil-d6 Fumarate
• Synonyms: 5-[[-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid-d6 1,9-Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate, GS 4331-05-d6, PMPA Prodrug-d6, Tenofovir DF-d6, Virea-d6, Viread-d6
• Brand: TRC
• Description: Stability HygroscopicApplications Isotope labelled Tenofovir Disoproxil Fumarate, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

Chemical properties

• Molecular weight: 525.4811607
• Formula: C₁₉H₂₄D₆N₅O₁₀P•C₄H₄O₄
• Color/Form: White To Off-White
• InChI: InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/i5D3,6D2,14D
• InChI key: InChIKey=VCMJCVGFSROFHV-NUWIOOBRSA-N
• SMILES: O=C(O)/C=C/C(=O)O.[2H]C([2H])([2H])C([2H])(OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C([2H])([2H])n1cnc2c(N)ncnc21