Product Information
Name:Tenofovir Disoproxil
Controlled Product
Synonyms:
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid
- 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
- 1,9-bis(1-methylethyl) ester
- 5-oxide
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid
- 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
- bis(1-me
Brand:TRC
Description:
Applications Tenofovir Disoproxil is a therapeutic option for nucleos(t)ide analog (NA)-experienced chronic hepatitis B (CHB) patients infected with hepatitis B virus (HBV). Also, it is an intermediate used in the synthesis of Tenofovir Disoproxil Dimer (T018515), which is a Tenofovir Disoproxil impurity.
References Huang, M., et al.: Clin. Drug Investig., 36, 471-478 (2016); Cheng, G., et al.: Chem. Res. Toxicol., 16, 145 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:519.443
Formula:C19H30N5O10P
Color/Form:Neat
InChI:InChI=1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m1/s1
InChI key:InChIKey=VPNHZIPMNHLIRB-ZETCQYMHSA-N
SMILES:Nc1cc(C[C@H](N)C(=O)O)cc(N)c1O
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