Testololactone

CAS: 4416-57-3

Ref. TR-T154805

Product Information

• Name: Testololactone
• Synonyms: (4aS,4bR,10aR,10bS,12aS)-3,4,4a,5,6,9,10,10a,10b,11,12,12a-Dodecahydro-10a,12a-dimethyl-2H-phenanthro[2,1-b]pyran-2,8(4bH)-dione, 13,17-Secoandrost-4-en-17-oic acid, 13-hydroxy-3-oxo-, δ-lactone (6CI,8CI), 13,17-Secoandrost-4-en-17-oic acid, 13α-hydroxy-3-oxo-, δ-lactone (7CI), D-Homo-17a-oxaandrost-4-ene-3,17-dione, 1,2,3,4,4a,4b,5,6,7,9,10,10a-Dodecahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic acid δ-lactone, 17a-Oxa-D-homoandrost-4-en-3,17-dione, 17a-Oxa-D-homoandrost-4-ene-3,17-dione, 2H-Phenanthro[2,1-b]pyran-2,8(4bH)-dione, 3,4,4a,5,6,9,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-, [4aS-(4aα,4bβ,10aβ,10bα,12aβ)]-
• Brand: TRC
• Description: Applications Testololactone, is the derivative of Testolactone (T154800), which is an antineoplastic agent that is a derivative of progesterone and is used to treat advanced stage breast cancer.References Dunkel, L.: Mol. Cell. Endocrinol., 254, 207 (2006); Eugster, E. A.: Treat. Endocrinol., 3, 141 (2004); Holbeck, S.L. et al.: Mol. Cancer Therap., 9, 1451 (2010)

Chemical properties

• Molecular weight: 302.41
• Formula: C₁₉H₂₆O₃
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C19H26O3/c1-18-9-7-13(20)11-12(18)3-4-14-15(18)8-10-19(2)16(14)5-6-17(21)22-19/h11,14-16H,3-10H2,1-2H3/t14-,15+,16+,18+,19+/m1/s1
• InChI key: InChIKey=CNIXJDVUMXTEKX-DZBHQSCQSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC(=O)O2