(2R)-Tetrahydro-2-furanmethanamine Hydrochloride

CAS: 7175-80-6

Ref. TR-T293555

Product Information

• Name: (2R)-Tetrahydro-2-furanmethanamine Hydrochloride
• Synonyms: (R)-Tetrahydro-2-furanmethanamine Hydrochloride, (R)-Tetrahydro-furfurylamine Hydrochloride, (-)-(R)-Tetrahydrofurfurylamine Hydrochloride, (2R)-2-Aminomethyltetrahydrofuran Hydrochloride, (2R)-Tetrahydrofuran-2-methanamine Hydrochloride, (R)-(-)-Tetrahydrofurfurylamine Hydrochloride, (R)-(Tetrahydrofuran-2-yl)methanamine Hydrochloride, (R)-1-(Tetrahydrofuran-2-yl)methylamine Hydrochloride, (R)-Tetrahydrofurfurylamine Hydrochloride, [((R)-Tetrahydrofuran-2-yl)methyl]amine Hydrochloride, [(R)-1-(Tetrahydro-furan-2-yl)]-methylamine Hydrochloride, [[(2R)-Tetrahydro-2-furanyl]methyl]amine Hydrochloride

Description

Stability Hygroscopic
Applications (2R)-Tetrahydro-2-furanmethanamine is a stereoisomer of Tetrahydro-2-furanmethanamine (T293545) which is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Tetrahydro-2-furanmethanamine (T293545) is also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 101.15 + 36.46
• Formula: C₅H₁₁NO·HCl
• Color/Form: Neat
• InChI: InChI=1S/C5H11NO.ClH/c6-4-5-2-1-3-7-5;/h5H,1-4,6H2;1H/t5-;/m1./s1
• InChI key: InChIKey=TUXSUKLRDNJDOR-NUBCRITNSA-N
• SMILES: Cl.NC[C@H]1CCCO1