3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-(methyl)-(3aR,5R,6S,7R,7aR)-5H-Pyrano[3,2-d]thiazole-6,7-diol-d3

CAS: 944070-25-1

Ref. TR-T293627

Product Information

• Name: 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-(methyl)-(3aR,5R,6S,7R,7aR)-5H-Pyrano[3,2-d]thiazole-6,7-diol-d3
• Synonyms: (3aR,5R,6S,7aR)-5-(hydroxymethyl)-2-(trideuteriomethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
• Brand: TRC

Description

Applications 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-(methyl-d3)-(3aR,5R,6S,7R,7aR)-5H-Pyrano[3,2-d]thiazole-6,7-diol-d3, is the labeled analogue of [3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano3,2-d]thiazole-6,7-diol (T293625), which can be used in the synthesis of Hexosaminidase inhibitors, which are the new drug candidates for the therapy of osteoarthritis.
References Liu, J. et al.: Chem. Bio., 8, 701 (2001);

Chemical properties

• Molecular weight: 222.277
• Formula: C₈D₃H₁₀NO₄S
• Color/Form: Neat
• InChI: InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6-,7?,8-/m1/s1/i1D3
• InChI key: InChIKey=DRHXTSWSUAJOJZ-JNWJRWOFSA-N
• SMILES: [2H]C([2H])([2H])C1=N[C@@H]2C(O)[C@H](O)[C@@H](CO)O[C@@H]2S1