(S)-Propyl Pramipexole

CAS: 1147937-31-2

Ref. TR-T293690

Product Information

• Name: (S)-Propyl Pramipexole
• Synonyms: (S)-N6,N6-Dipropyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine, (6S)-4,5,6,7-Tetrahydro-N6,N6-dipropyl-2,6-benzothiazolediamine

Description

Applications (S)- Propyl Pramipexole is (S)-Pramipexole (P700750) analogue. (S)-Pramipexole (P700750) is a dopamine-D2-receptor agonist. Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
References Mierau, J., et al.: J. Med. Chem., 30, 494 (1987);Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992);Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997);

• Brand: TRC

Chemical properties

• Molecular weight: 253.41
• Formula: C₁₃H₂₃N₃S
• Color/Form: Neat
• InChI: InChI=1S/C13H23N3S/c1-3-7-16(8-4-2)10-5-6-11-12(9-10)17-13(14)15-11/h10H,3-9H2,1-2H3,(H2,14,15)/t10-/m0/s1
• InChI key: InChIKey=ABRFKTAFRQVZBR-JTQLQIEISA-N
• SMILES: CCCN(CCC)[C@H]1CCc2nc(N)sc2C1