1,2,3,4-Tetrahydro-5-(2-oxiranylmethoxy)-(2R,3S)-rel-2,3-naphthalenediol-D5

CAS: 627081-12-3

Ref. TR-T295852

Product Information

• Name: 1,2,3,4-Tetrahydro-5-(2-oxiranylmethoxy)-(2R,3S)-rel-2,3-naphthalenediol-D5
• Synonyms: (2R,3S)-5-[dideuterio-(2,3,3-trideuteriooxiran-2-yl)methoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol

Description

Applications 1,2,3,4-Tetrahydro-5-(2-oxiranylmethoxy)-(2R,3S)-rel-2,3-naphthalenediol-D5 is an isotopic labelled analog of 1,2,3,4-tetrahydro-5-(2-oxiranylmethoxy)-(2R,3S)-rel-2,3-naphthalenediol. 1,2,3,4-Tetrahydro-5-(2-oxiranylmethoxy)-(2R,3S)-rel-2,3-naphthalenediol is used as a reactant in the synthetic preparation of Nadolol (cis-5-{3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy}-1,2,3,4-tetrahydro-2,3-naphthalenediol) which is a β-adrenergic blocking agent.
References Lacroix, P., et al.: J. Pharm. Biomed. Anal., 10, 917 (1992), Lee, S., et al.: J. Food Sci., 72, S497 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 241.295
• Formula: C₁₃D₅H₁₁O₄
• Color/Form: Neat
• InChI: InChI=1S/C13H16O4/c14-11-4-8-2-1-3-13(10(8)5-12(11)15)17-7-9-6-16-9/h1-3,9,11-12,14-15H,4-7H2/t9?,11-,12+/m1/s1/i6D2,7D2,9D
• InChI key: InChIKey=OAFYUCDEFSNRJA-ASIFHRLFSA-N
• SMILES: [2H]C([2H])(Oc1cccc2c1C[C@H](O)[C@H](O)C2)C1([2H])OC1([2H])[2H]