Product Information
- Medronic Acid Imp. B (EP)
- P,P'-Methylenebisphosphonic acid
- Phosphonic acid
- methylenebis-
- tetrakis(1-methylethyl) ester (9CI)
- Phosphonic acid
- methylenedi-
- tetraisopropyl ester (7CI,8CI)
- Methylenediphosphonic acid tetraisopropyl ester
- NSC 226577
- See more synonyms
- Tetraisopropyl methylenebisphosphonate
- Tetrakis(O-isopropyl) methylenediphosphonate
- [(Diisopropoxyphosphinyl)methyl]diisopropoxyphosphine oxide
- Medronic Acid Impurity B
- 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
- Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester
- Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
- Phosphonic acid, methylenedi-, tetraisopropyl ester
- Tetraisopropylmethylenediphosphonate
- Tetrapropan-2-Yl Methanediylbis(Phosphonate)
Applications Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.
References Wang, G. et al.: J. Med. Chem., 47, 6902 (2004); Gil, L. et al.: Bioorg. Med. Chem., 7, 901 (1999);
Chemical properties
Technical inquiry about: TR-T296270 Tetraisopropyl Methylenediphosphonate
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