2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid

CAS: 164265-78-5

Ref. TR-T308515

Product Information

• Name: 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid
• Synonyms: [1,1'-Biphenyl]-4-carboxylic acid, 2'-(2H-tetrazol-5-yl)-, [1,1'-Biphenyl]-4-carboxylic acid, 2'-(1H-tetrazol-5-yl)- (9CI), Valsartanic Acid

Description

Stability Hygroscopic
Applications 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is a transformation product of Valsartan (V095750); a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid.
References Noedler, K., et al.: Water Res., 47, 6650 (2013); Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 266.25
• Formula: C₁₄H₁₀N₄O₂
• Color/Form: White To Off-White
• InChI: InChI=1S/C14H10N4O2/c19-14(20)10-7-5-9(6-8-10)11-3-1-2-4-12(11)13-15-17-18-16-13/h1-8H,(H,19,20)(H,15,16,17,18)
• InChI key: InChIKey=USAWIVMZUYOXCF-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1