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Tezosentan
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Tezosentan

CAS: 180384-57-0

Ref. TR-T321500

50mg
30,076.00 €
Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
Tezosentan
Controlled Product
Synonyms:
  • N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide
  • 2-Pyridinesulfonamide, N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)-4-pyridinyl)-4-pyrimidinyl)-5-(1-methylethyl)-
  • 2-Pyridinesulfonamide, N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-
  • Act 050089
  • N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)-4-pyridinyl)-4-pyrimidinyl)-5-(1-methylethyl)-2-pyridinesulfonamide
  • N-(6-(2-Hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)-4-pyridyl)-4-pyrimidinyl)-5-isopropyl-2-pyridinesulfonamide
  • N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4yl]pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide
  • N-{6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl}-5-(propan-2-yl)pyridine-2-sulfonamide
  • Ro 61-6612
  • Ro 610612
  • See more synonyms
  • Tezosentan [INN]
  • Unii-64J9J55263
Description:

Applications A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900). It is used in the treatment of congestive heart failure.
References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 290, 840 (1999), Dingemanse, J., et al.: Br. J. Clin. Pharmacol., 53, 355 (2002), Schalcher, C., et al.: Am. Heart J., 142, 340 (2001),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
605.625
Formula:
C27H27N9O6S
Color/Form:
Neat
InChI:
InChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)
InChI key:
InChIKey=HLMUYZYLPUHSNV-PKLMIRHRSA-N
SMILES:
Cc1ccc(S(=O)(=O)O)cc1.N[C@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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