Product Information
Name:Tezosentan
Controlled Product
Synonyms:
- N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide
Brand:TRC
Description:Applications A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900). It is used in the treatment of congestive heart failure.References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 290, 840 (1999), Dingemanse, J., et al.: Br. J. Clin. Pharmacol., 53, 355 (2002), Schalcher, C., et al.: Am. Heart J., 142, 340 (2001),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:605.625
Formula:C27H27N9O6S
Color/Form:Neat
InChI:InChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)
InChI key:InChIKey=HLMUYZYLPUHSNV-PKLMIRHRSA-N
SMILES:Cc1ccc(S(=O)(=O)O)cc1.N[C@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1
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