Product Information
Name:TG101209-d9
Controlled Product
Synonyms:
- N-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
Brand:TRC
Description:Applications TG101209-d9 is the isotope labelled analog of TG101209 (T337900); an effective tyrosine kinase inhibitor of tyrosine kinases JAK2 and JAK3 (janus kinase 2/3), inducing cell arrest and apoptosis in leukemia cell lines.References Samanta, A. et al.: Leukemia, 25, 463 (2011); Traer, E. et al.: Leukemia, 26, 1140 (2012); Ramakrishnan, V. et al.: Am. J. Hematol., 85, 675 (2010)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:518.722
Formula:C26D9H26N7O2S
Color/Form:Neat
InChI:InChI=1S/C26H35N7O2S/c1-19-18-27-25(29-20-9-11-22(12-10-20)33-15-13-32(5)14-16-33)30-24(19)28-21-7-6-8-23(17-21)36(34,35)31-26(2,3)4/h6-12,17-18,31H,13-16H2,1-5H3,(H2,27,28,29,30)/i2D3,3D3,4D3
InChI key:InChIKey=JVDOKQYTTYUYDV-WVZRYRIDSA-N
SMILES:[2H]C([2H])([2H])C(NS(=O)(=O)c1cccc(Nc2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2C)c1)(C([2H])([2H])[2H])C([2H])([2H])[2H]
Technical inquiry about: TG101209-d9
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