Thalidomide

CAS: 50-35-1

Ref. TR-T338850

Product Information

• Name: Thalidomide
• Synonyms: 2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline, 3-Phthalimidoglutarimide, Celgene, Contergan, Distaval, K 17, Kevadon, Myrin, N-(2,6-Dioxo-3-piperidyl)phthalimide, N-Phthaloylglutamimide, NSC 527179, NSC 66847, Neurosedyn, Pantosediv, Pharmion, Quetimid, Sauramide, Sedalis, Sedoval, Softenil, Softenon, Suaramide, Synovir, Talimol, Talinol, Thaled, Thalomid, alpha-(N-Phthalimido)glutarimide, alpha-N-Phthalylglutaramide, alpha-Phthalimidoglutarimide, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, 2-(2,6-Dioxo-3-Piperidinyl)-1H-Isoindole-1,3(2H)-Dione, 2-(2,6-Dioxo-piperidin-3-yl)-isoindole-1,3-dione, 2-(2,6-Dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione, 2-(2,6-Dioxopiperidin-3-yl)isoindole-1,3-dione, 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione, 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione, 2-Phthalimidoglutarimide, Immunoprin, N-(2,6-Dioxo-3-piperidinyl)phthalimide, Nsc 527179, Nsc 66847, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, Talidomida, Thalidomid, α-(N-Phthalimido)glutarimide, α-N-Phthalylglutaramide, α-Phthalimidoglutarimide

Description

Applications Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)

• Brand: TRC

Chemical properties

• Molecular weight: 258.23
• Formula: C₁₃H₁₀N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
• InChI key: InChIKey=UEJJHQNACJXSKW-UHFFFAOYSA-N
• SMILES: O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1