Thiocolchicoside

CAS: 602-41-5

Ref. TR-T344385

Product Information

• Name: Thiocolchicoside
• Synonyms: Colchicoside, thio- (6CI,7CI), Benzo[a]heptalene, acetamide deriv., 2-Demethoxy-2-glucosidoxythiocolchicine, Coltramyl, Coltrax, Etoshine MR, Miorel, Miotens, Muscoril, NSC 147755, R 271, Thiocholshikoside, Thiocolchicoside,Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, Acetamide, N-[3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)-, Colchicoside
• Brand: TRC

Description

Applications A GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects.
References Gelmi, M., et al.: J. Med. Chem., 50, 2245 (2007), Mascia, M., et al.: Eur. J. Pharmacol., 558, 37 (2007), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Chemical properties

• Molecular weight: 563.62
• Formula: C₂₇H₃₃NO₁₀S
• Color/Form: Neat
• InChI: InChI=1S/C27H33NO10S/c1-12(30)28-16-7-5-13-9-18(37-27-24(34)23(33)22(32)19(11-29)38-27)25(35-2)26(36-3)21(13)14-6-8-20(39-4)17(31)10-15(14)16/h6,8-10,16,19,22-24,27,29,32-34H,5,7,11H2,1-4H3,(H,28,30)/t16-,19+,22+,23-,24+,27+/m0/s1
• InChI key: InChIKey=ODABCKMSNZLGFO-HNNXBMFYSA-N
• SMILES: COc1ccc(OC)c2c1CC[C@@](NC(C)=O)(C(=O)O)C2