Product Information
Name:Thromboxane B2
Controlled Product
Synonyms:
- 8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid Hemiacetal
- (5Z,9α,13E,15S)9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid
- TXB2
- (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid
Brand:TRC
Description:Applications An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.References Needleman, P. et al.: Nature, 261, 558 (1976); Patrono, C. et al.: J Clin. Invest., 77, 590 (1986); Patrono, C. et al.: Adv. Prostaglandin Thromboxane Leukot. Res., 11, 493 (1983);
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Chemical properties
Molecular weight:370.48
Formula:C20H34O6
Color/Form:Neat
InChI:InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1
InChI key:InChIKey=XNRNNGPBEPRNAR-DFWOEQORSA-N
SMILES:CCCCCC(O)/C=C/[C@H]1OC(O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O
Technical inquiry about: Thromboxane B2
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