Thyrotropin-Releasing Hormone

CAS: 24305-27-9

Ref. TR-T413510

Product Information

• Name: Thyrotropin-Releasing Hormone
• Synonyms: Protirelin, 5-Oxo-l-prolyl-l-histidyl-l-prolinamide, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, Thyrotropin-releasing factor (8CI), (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2, 252: PN: WO2010033207 SEQID: 378 claimed protein, 83: PN: US20090175821 PAGE: 403 claimed protein, Abbott 38579, Antepan, FDA 1725, L-Pyroglutamyl-L-histidyl-L-prolinamide, L-Pyroglutamyl-L-histidyl-L-proline amide, Lopremone, Prem, Protirelin, Relefact TRH, Rifathyroin, Rifotironin, Ro 8-6270/9, Stimu TSH, Synthetic TRF, Synthetic TRH, Synthetic TSH-releasing factor, Synthetic TSH-releasing hormone, Synthetic thyrotropin-releasing factor, Synthetic thyrotropin-releasing hormone, TRF, TRH, TSH-RF, TSH-releasing factor, TSH-releasing hormone, Thypinone, Thyrefact, Thyroid releasing hormone, Thyroid-stimulating hormone-releasing factor, Thyroliberin, Thyrotropic hormone-releasing factor, Thyrotropic hormone-releasing hormone, Thyrotropic releasing hormone, Thyrotropic-releasing factor, (Pyro)-<span class="text-smallcaps">L</smallcap>-glutamic acid-<smallcap>L</smallcap>-histidine-<smallcap>L</span>-proline-NH₂, 5-Oxo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, <span class="text-smallcaps">L</smallcap>-Prolinamide, 5-oxo-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-histidyl-, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline amide, Fda 1725, Protirelina, Protireline, Thyrotropin-releasing factor, Thyrotropin-releasing hormone, Tsh-Rf, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, 5-Oxo-L-prolyl-L-histidyl-L-prolinamide

Description

Applications Thyrotropin-Releasing Hormone is a hypothalamic hypophysiotropic neuropeptide, which has the ability to stimulate the release of thyroid-stimulating hormone in mammals. It is proven that Thyrotropin-Releasing Hormone can be used to accelerate wound healing.
References Kanasaki, H., et al.: Neuropeptides., 54, 73 (2015); Nie, C., et al.: J. Surg. Res., 189, 364 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 362.38
• Formula: C₁₆H₂₂N₆O₄
• Color/Form: Off-White
• InChI: InChI=1S/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/t10-,11-,12-/m0/s1
• InChI key: InChIKey=XNSAINXGIQZQOO-SRVKXCTJSA-N
• SMILES: NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1