Thyroxine Sodium Salt

CAS: 55-03-8

Ref. TR-T425601

Product Information

• Name: Thyroxine Sodium Salt
• Synonyms: L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1), L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt (9CI), Thyroxine, monosodium salt, L- (8CI), Berlthyrox, Dathroid, Droxine, Eferox, Elthyrone, Elthyroxine, Eltroxin, Euthyrox, Eutirox, L-Thyroxin Henning, L-Thyroxine monosodium salt, L-Thyroxine sodium, L-Thyroxine sodium salt, Laevoxin, Letrox, Letter, Levaxin, Leventa, Levo-T, Levolet, Levoroxine, Levothroid, Levothyrox, Levothyroxine sodium, Levotirox, Levotiroxina, Levoxyl, Monosodium thyroxine, NSC 259940, Novothyrox, Oroxine, Puran T 4, Sodium L-thyroxine, Sodium levothyroxine, Sodium thyroxin, Sodium thyroxinate, Sodium thyroxine, Synthroid, Synthroid sodium, Synthrox, T 4KP, T4 Montpellier 100, Thevier, Throxinique, Thyradin, Thyradin S, Thyrax Duotab, Thyrex, Thyro 4, Thyrosit, Thyroxevan, Thyroxine sodium, Tiroidine, Tirosint, Unithroid, Levothyroxine Sodium Salt, <span class="text-smallcaps">L</span>-Thyroxin Henning, <span class="text-smallcaps">L</span>-Thyroxine monosodium salt, <span class="text-smallcaps">L</span>-Thyroxine sodium, <span class="text-smallcaps">L</span>-Thyroxine sodium salt, <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1), Sodium 2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]Propanoate, Sodium 4-O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine, Sodium <span class="text-smallcaps">L</span>-thyroxine, T 4Kp, Thyroxine sodium salt, Thyroxine, monosodium salt, <span class="text-smallcaps">L</span>-, tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)

Description

Stability Hygroscopic
Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),

• Brand: TRC

Chemical properties

• Molecular weight: 798.85
• Formula: C₁₅H₁₀I₄NO₄·Na
• Color/Form: Neat
• InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m0./s1
• SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c([O-])c(I)c2)c(I)c1)C(=O)O.[Na+]