Product Information
Name:D-Thyroxine
Controlled Product
Synonyms:
- D-Tyrosine
- O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
- Thyroxine
- D- (8CI)
- 3,3',5,5'-Tetraiodo-D-thyronine
- D-T4
- Dextrothyroxine
Brand:TRC
Description:Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),
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Chemical properties
Molecular weight:776.87
Formula:C15H11I4NO4
Color/Form:Off-White To Beige
InChI:InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m1/s1
InChI key:InChIKey=XUIIKFGFIJCVMT-GFCCVEGCSA-N
SMILES:N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O
Technical inquiry about: D-Thyroxine
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