∆4-Tibolone-13C,d3

CAS: 1162-60-3

Ref. TR-T437507

Product Information

• Name: ∆4-Tibolone-13C,d3
• Synonyms: (7a,17a)-17-Hydroxy-7-(methyl-13C,d3)-19-norpregn-4-en-20-yn-3-one, 17a-Ethynyl-17-hydroxy-7a-(methyl-13C,d3)-4-estren-3-one, 7a-Methylnorethindrone-13C,d3, NSC 142228-13C,d3, Org-OM 38-13C,d3, (7Alpha)-17-Ethynyl-17-Hydroxy-7-Methylestr-4-En-3-One, (7a,17a)-17-Hydroxy-7-methyl-19-norpregn-4-en-20-yn-3-one, 17-Ethynyl-17-Hydroxy-7-Methylestr-4-En-3-One, 17a-Ethynyl-17-hydroxy-7a-methyl-4-estren-3-one, 17β-Hydroxy-17α-ethynyl-7α-methylestr-4-en-3-one, 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-hydroxy-7α-methyl-, 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-7-methyl-, (7α,17α)-, 7a-Methylnorethindrone, 7α-Methyl-17α-ethynyl-19-nortestosterone, Isotibolone, Nsc 142228, Org-OM 38, Δ⁴-Tibolone

Description

Applications A labelled metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.
References Clarkson, T., et al.: J. Clin. Endocrinol. Metab., 86, 5396 (2001), Landgren, M., et al.: Maturitas, 50, 222 (2005), Wang, M., et al.: Steroids, 71, 343 (2006), Verheul, H., et al.: Drug Metab. Dispos., 35, 1105 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 316.46
• Formula: C₂₀₁₃CH₂₅D₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,12-13,16-19,23H,5-11H2,2-3H3/t13-,16+,17-,18+,19-,20+,21+/m1/s1/i2+1D3
• SMILES: [2H][13C]([2H])([2H])[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]3(O)C#C)[C@@H]21