Tigecycline Pentacyclic Analog, Technical Grade

CAS: 1268494-40-1

Ref. TR-T440030

Product Information

• Name: Tigecycline Pentacyclic Analog, Technical Grade
• Synonyms: (1S,4aR,4bR,10aR,11aS)-9-(Dimethylamino)-7-[[2-[(1,1-dimethylethyl)amino]acetyl]amino]-1,2,4a,5,10,10a,11,11a-octahydro-1,4,4a,6-tetrahydroxy-2,5,12-trioxo-1,4b-methano-4bH-benzo[b]fluorene-3-carboxamide, Tigecycline Pentacyclic Analog,
• Brand: TRC
• Description: Applications Tigecycline pentacyclic analog is an impurity of Tigecycline (T440015), one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline.References Grosse, E., et al.: Clin. Infect. Dis. (Supplement 5), 41, S341 (2005); Livermore, D.: J. Antimicrob. Chemoth., 56, 611 (2005); Stein, G. & Craig, W.: Clin. Infect. Dis., 43, 518 (2006)

Chemical properties

• Molecular weight: 556.56
• Formula: C₂₇H₃₂N₄O₉
• Color/Form: Neat
• InChI: InChI=1S/C27H32N4O9/c1-24(2,3)29-9-15(32)30-12-8-13(31(4)5)11-6-10-7-14-26(39)20(35)17(22(28)37)21(36)27(14,40)25(10,23(26)38)19(34)16(11)18(12)33/h8,10,14,29,33,36,39-40H,6-7,9H2,1-5H3,(H2,28,37)(H,30,32)
• InChI key: InChIKey=FBVQSWIWHMQLGD-UHFFFAOYSA-N
• SMILES: CN(C)c1cc(NC(=O)CNC(C)(C)C)c(O)c2c1CC1CC3C4(O)C(=O)C(C(N)=O)=C(O)C3(O)C1(C2=O)C4=O