(R)-Timolol

CAS: 26839-76-9

Ref. TR-T443695

Product Information

• Name: (R)-Timolol
• Synonyms: (+)-Timolol, L 714465, d-Timolol, (R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol, (+)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol, Timolol EP Impurity A, Timolol BP Impurity A, Timolol USP Related Compound A, (2R)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol, (2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol, (R)-(+)-Timolol, 1,2,5-Thiadiazole, 2-propanol deriv., 1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propanol, 2-Propanol, 1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-, 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2R)-, 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (R)-, (+)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Description

Impurity Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A
Applications (R)-Timolol (Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A) is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.
References Rotmensch, H. et al.: J. Clinical. Pharmacol., 33, 544 (1993); Chiou, G. & Chen. Y., J. Ocular. Pharmacol., 8, 183 (1992); Chiou, G. et al.: J. Ocular. Pharmacol., 6, 23 (1990); Tocco, D. et al.: Drug Met. Disposit., 4, 323 (1976)

• Brand: TRC

Chemical properties

• Molecular weight: 316.42
• Formula: C₁₃H₂₄N₄O₃S
• Color/Form: Neat
• InChI: InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m1/s1