Product Information
Name:TIQ-A
Controlled Product
Synonyms:
- 4H-thieno[2,3-c]isoquinolin-5-one
Brand:TRC
Description:Applications A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).References Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:201.24
Formula:C11H7NOS
Color/Form:Brown To Dark Blue
InChI:InChI=1S/C11H7NOS/c13-10-8-4-2-1-3-7(8)9-5-6-14-11(9)12-10/h1-6H,(H,12,13)
InChI key:InChIKey=LQJVOLSLAFIXSV-UHFFFAOYSA-N
SMILES:O=c1[nH]c2sccc2c2ccccc12
Technical inquiry about: TIQ-A
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