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Product Information
Name:
Tofacitinib impurity L
Controlled Product
Synonyms:
- (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-ß-oxo-1-piperidinepropanamide
- Tofacitinib Citrate Impurity 05
Description:
Impurity Tofacitinib Impurity (T528000)
Applications Tofacitinib impurity L is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
330.38
Formula:
C16H22N6O2
Color/Form:
Neat
InChI:
InChI=1S/C16H22N6O2/c1-10-4-6-22(14(24)7-13(17)23)8-12(10)21(2)16-11-3-5-18-15(11)19-9-20-16/h3,5,9-10,12H,4,6-8H2,1-2H3,(H2,17,23)(H,18,19,20)/t10-,12+/m1/s1
InChI key:
InChIKey=CRDMXSMPTHMXRD-PWSUYJOCSA-N
SMILES:
C[C@@H]1CCN(C(=O)CC(N)=O)C[C@@H]1N(C)c1ncnc2[nH]ccc12
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-T528015 Tofacitinib impurity L
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