Torcetrapib

CAS: 262352-17-0

Ref. TR-T546500

Product Information

• Name: Torcetrapib
• Synonyms: (2R,4S)-4-[[[3,5-Bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-1(2H)-quinolinecarboxylic Acid Ethyl Ester, CP 529414, (2R,4S)-4-[(3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester, (2R,4S)-4-[[3,5-Bis(trifluoromethyl)benzyl]methoxycarbonylamino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester, 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-, Cp 529414, ethyl (2R,4S)-4-{[3,5-bis(trifluoromethyl)benzyl](methoxycarbonyl)amino}-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate
• CAS: 262352-17-0

Description

Applications Cholesteryl ester transfer protein (CETP) inhibitor. Antilipemic; antiatherosclerotic.
References Burnett, J.R., et al.: Curr. Opin. Invest. Drugs, 6, 944 (2005), Clark, R.W., et al.: J. Lipid Res., 47, 537 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 600.47
• Formula: C₂₆H₂₅F₉N₂O₄
• Color/Form: White to Pale Yellow Solid
• InChI: InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15+,17?,18+/m1/s1
• InChI key: InChIKey=KXNPVXPOPUZYGB-COJCKYOVSA-N
• SMILES: C[C@@H]1CNc2c(cccc2S(=O)(=O)NC(CCCNC(=N)N)C(=O)N2CC[C@@H](C)C[C@H]2C(=O)O)C1