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Product Information
Name:
Tozasertib
Controlled Product
Synonyms:
- N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
- Cyclopropanecarboxylic acid N-[4-[[4-(4-methylpiperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)pyrimidin-2-yl]sulfanyl]phenyl]amide
- Mk 0457
- N-[4-({4-(4-Methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide
- N-[4-({4-(4-Methylpiperazin-1-yl)-6-[(3-methyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}sulfanyl)phenyl]cyclopropanecarboxamide
- N-[4-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}sulfanyl)phenyl]cyclopropanecarboxamide
- N-[4-[[4-(4-Methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide
- cyclopropanecarboxamide, N-[4-[[4-(4-methyl-1-piperazinyl)-6-[(3-methyl-1H-pyrazol-5-yl)amino]-2-pyrimidinyl]thio]phenyl]-
- cyclopropanecarboxamide, N-[4-[[4-(4-methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]-
- VX 680
- See more synonyms
Description:
Applications A multikinase inhibitor once used for cancer treatment.
References Ulisse, S., et al.: J. Endocrinol., 204, 135 (2010), McDermott, U., et al.: Cancer Res., 70, 1625 (2010), Donato, N., et al.: Biochem., Pharmacol., 79, 688 (2010),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
464.59
Formula:
C23H28N8OS
Color/Form:
Neat
InChI:
InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)
InChI key:
InChIKey=GCIKSSRWRFVXBI-UHFFFAOYSA-N
SMILES:
Cc1cc(=Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)[nH][nH]1
MDL:
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EINECS:
Merck:
HS code:
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