Product Information
Name:TQS
Controlled Product
Synonyms:
- 3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopenta[c]quinoline-8-sulfonamide
Brand:TRC
Description:Applications TQS is a positive allosteric modulator (Type II) of alpha7 nACh receptors, functional human α7 nicotinic acetylcholine receptor (nAChR) generated from Escherichia coli that opens a new avenue for producing mammalian Cys-loop receptors to facilitate structure-based rational drug design.References Tillman, T. S., et al.: J. Biol. Chem., 291, 18276 (2016)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:376.47
Formula:C22H20N2O2S
Color/Form:Neat
InChI:InChI=1S/C22H20N2O2S/c23-27(25,26)15-11-12-21-20(13-15)17-8-4-10-19(17)22(24-21)18-9-3-6-14-5-1-2-7-16(14)18/h1-9,11-13,17,19,22,24H,10H2,(H2,23,25,26)
InChI key:InChIKey=SIZWDJIHABLBSP-UHFFFAOYSA-N
SMILES:NS(=O)(=O)c1ccc2c(c1)C1C=CCC1C(c1cccc3ccccc13)N2
Technical inquiry about: TQS
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