Triamcinolone 16,21-Diacetate

CAS: 67-78-7

Ref. TR-T767170

Product Information

• Name: Triamcinolone 16,21-Diacetate
• Synonyms: Triamcinolone Imp. A (EP), Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-, 16,21-diacetate (6CI,7CI,8CI), (11beta,16alpha)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, 16alpha,21-Diacetoxy-9alpha-fluoro-11beta,17alpha-dihydroxy-1,4-pregnadiene-3,20-dione, 16alpha-Hydroxy-9alpha-fluoroprednisolone diacetate, 8357RP, 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,21-diacetate, 9alpha-Fluoro-1,4-pregnadiene-11beta,16alpha,17alpha,21-tetraol-3,20-dione 16,21-diacetate, 9alpha-Fluoro-16alpha-hydroxyprednisolone 16,21-diacetate, Aristocort Forte, Aristocort Forte Parenteral, Aristocort Parenterals, Aristocort Syrup, Aristocort diacetate forte, Aristocort diacetate parenteral, CINO 40, Cenacort, Kenacort diacetate Syrup, Kenacourt, Orion, Polcortolon, TAC-D, Tedarol, Tracilon, Triamcinolone diacetate, Triamolone 40, Delta1-16alpha-Hydroxy-9alpha-fluorohydrocortisone diacetate, Delta1-9alpha-Fluoro-16alpha-hydroxyhydrocortisone diacetate, Triamcinolone Impurity A, (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Diene-16,21-Diyl Diacetate, (11β,16α)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Diene-16,21-Diyl Diacetate, 16-(Acetyloxy)-9-fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, 16α,21-Diacetoxy-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione, 16α-Hydroxy-9α-fluoroprednisolone diacetate, 21-Diacetate, 8357Rp, 9-Alpha-Fluoro-16-Alpha-Hydroxyprednisolonediacetate, 9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Diene-16,21-Diyl Diacetate, 9-Fluoro-11-Beta,16-Alpha,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione16,21, 9-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,21-diacetate, 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,21-diacetate, 9-alpha-Fluoro-16-alpha-hydroxyprednisolone diacetate, 9α-Fluoro-1,4-pregnadiene-11β,16α,17α,21-tetraol-3,20-dione 16,21-diacetate, 9α-Fluoro-16α-hydroxyprednisolone 16,21-diacetate, Aristocort diacetate-, Cino 40, Pregna-1,4-diene-3,20-dione, 16,21-bis(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, 16,21-diacetate, Tac-D, Triamcinolone 16,21-diacetate, Δ¹-16α-Hydroxy-9α-fluorohydrocortisone diacetate, Δ¹-9α-Fluoro-16α-hydroxyhydrocortisone diacetate

Description

Applications A glucocorticoid that inhibits prolyl hydroxylase activity and used as an antiasthmatic and antiallergic drug.
References Kos-Kudla, B. et al.; J. Clin. Pharm. Ther., 28, 103 (2003); Hochhaus, G. et al.; Pharmaceut. Res., 7, 558 (1990); Counts, D. et al.: Mol. Pharmacol., 15, 99 (1979); Cutroneo, K. et al.; Mol. Pharmacol., 11, 632 (1975); Cutroneo, K. et al.: Mol. Pharmacol., 11, 44 (1975)

• Brand: TRC

Chemical properties

• Molecular weight: 478.51
• Formula: C₂₅H₃₁FO₈
• Color/Form: Neat
• InChI: InChI=1S/C25H31FO8/c1-13(27)33-12-20(31)25(32)21(34-14(2)28)10-18-17-6-5-15-9-16(29)7-8-22(15,3)24(17,26)19(30)11-23(18,25)4/h7-9,17-19,21,30,32H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-,25+/m0/s1
• InChI key: InChIKey=XGMPVBXKDAHORN-RBWIMXSLSA-N
• SMILES: CC(=O)OCC(=O)[C@@]1(O)[C@H](OC(C)=O)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C