2,2,2-Trichloroethyl Chloroformate

CAS: 17341-93-4

Ref. TR-T774340

Product Information

• Name: 2,2,2-Trichloroethyl Chloroformate
• Synonyms: Carbonochloridic Acid 2,2,2-Trichloroethyl Ester, Chloro-formic Acid 2,2,2-Trichloroethyl Ester, 2,2,2-Trichloro-ethanol Chloroformate, (Trichloroethoxy)chloroformate, 2,2,2-Trichloroethoxycarbonyl Chloride, Chloroformic Acid 2,2,2-Trichloroethyl Ester, NSC 152038, Troc-Cl, beta,beta,beta-Trichloroethoxycarbonyl Chloride, beta,beta,beta-Trichloroethyl Chloroformate
• Brand: TRC
• Description: Applications 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Montzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974); Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014); Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)

Chemical properties

• Molecular weight: 211.86
• Formula: C₃H₂Cl₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: CCOC(=O)CC#N