2,5-Thiazolylmethyl Diacarbonate

CAS: 144142-33-6

Ref. TR-T779365

Product Information

• Name: 2,5-Thiazolylmethyl Diacarbonate
• Synonyms: Carbamic acid, N,N'-[(1S,2S,4S)-2-hydroxy-1,4-bis(phenylmethyl)-1,4-butanediyl]bis-, C,C'-bis(5-thiazolylmethyl) ester, Carbamic acid, [(1S,2S,4S)-2-hydroxy-1,4-bis(phenylmethyl)-1,4-butanediyl]bis-, bis(5-thiazolylmethyl) ester (9CI), Carbamic acid, [2-h
• Brand: TRC
• Description: Applications 2,5-Thiazolylmethyl Diacarbonate is an impurity of Ritonavir (R535000), a selective HIV protease inhibitor.References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003); Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006); Koppala, S., et al.: J. Chromatogr. Sci., 53, 662 (2015)

Chemical properties

• Molecular weight: 566.692
• Formula: C₂₈H₃₀N₄O₅S₂
• Color/Form: Neat
• InChI: InChI=1S/C28H30N4O5S2/c33-26(25(12-21-9-5-2-6-10-21)32-28(35)37-17-24-15-30-19-39-24)13-22(11-20-7-3-1-4-8-20)31-27(34)36-16-23-14-29-18-38-23/h1-10,14-15,18-19,22,25-26,33H,11-13,16-17H2,(H,31,34)(H,32,35)/t22-,25-,26-/m0/s1
• InChI key: InChIKey=GXCDHFBSVILEOW-HRNNMHKYSA-N
• SMILES: O=C(N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1)OCc1cncs1