Product Information
Name:Triciribine phosphate
Controlled Product
Synonyms:
- 1,5-Dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-1,4,5,6,8-pentaazaacenaphthylen-3-amine
- 1,4,5,6,8-Pentaazaacenaphthylene-3-amino-1,5-dihydro-5-methyl-1-β-D-ribofuranosyl 5'-monophosphate
- NSC 280594
- TCN-P
- VQD 002
Brand:TRC
Description:Applications Triciribine phosphate is an Akt activation inhibitor that inhibits Akt phosphorylation by binding to the pleckstrin homology (PH) domain of the Akt and blocking its recruitment to the plasma membrane.References Berndt, N., et al.: Cell Death Differ. 17, 1795 (2010)
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Chemical properties
Molecular weight:400.284
Formula:C13H17N6O7P
Color/Form:Neat
InChI:InChI=1S/C13H17N6O7P/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(21)8(20)6(26-13)3-25-27(22,23)24/h2,4,6,8-9,13,20-21H,3H2,1H3,(H2,14,17)(H2,22,23,24)/t6-,8-,9-,13-/m1/s1
InChI key:InChIKey=URLYINUFLXOMHP-HTVVRFAVSA-N
SMILES:CN1N=C(N)c2cn([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O)c3ncnc1c23
Technical inquiry about: Triciribine phosphate
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