N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

CAS: 42267-27-6

Ref. TR-T788530

Product Information

• Name: N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
• Synonyms: Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-, Acetamide, N-[4-(2,5-dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoro-, (S)-, N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide, N-Trifluoroacetyl-L-lysine N-carboxyanhydride, Ne-Trifluoroacetyl-L-lysine N-carboxyanhydride, (S)-N-(4-(2,5-dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide, Acetamide, N-[4-(2,5-dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoro-, (S)-, Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-, H-Lys(Tfa)-Nca, N-Trifluoroacetyl-<span class="text-smallcaps">L</span>-lysine N-carboxyanhydride, N-[4-[(4S)-2,5-Dioxooxazolidin-4-Yl]Butyl]-2,2,2-Trifluoro-Acetamide, N-{4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide, N^ε-Trifluoroacetyl-<span class="text-smallcaps">L</span>-lysine N-carboxyanhydride

Description

Applications Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.
References Svenson, S., et al.: Adv. Drug Delivery Rev., 57, 2106 (2005), Shen, X., et al.: Org. Biomol. Chem., 5, 3674 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 268.19
• Formula: C₉H₁₁F₃N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
• InChI key: InChIKey=KWNIHCJDDYRQFW-YFKPBYRVSA-N
• SMILES: O=C1N[C@@H](CCCCNC(=O)C(F)(F)F)C(=O)O1