N-2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethylsilodosin

CAS: 1453221-45-8

Ref. TR-T790140

Product Information

• Name: N-2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethylsilodosin
• Synonyms: 5-[(2R)-2-[Bis[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-dihydro-1-(3-hydroxypropyl)-1H-indole-7-carboxamide
• Brand: TRC
• Description: Applications An impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.References Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995), Murata, S., et al.: J. Urol., 164, 578 (2000),

Chemical properties

• Molecular weight: 713.71
• Formula: C₃₅H₄₁F₆N₃O₆
• Color/Form: Neat
• InChI: InChI=1S/C35H41F6N3O6/c1-24(19-25-20-26-11-13-44(12-6-16-45)32(26)27(21-25)33(42)46)43(14-17-47-28-7-2-4-9-30(28)49-22-34(36,37)38)15-18-48-29-8-3-5-10-31(29)50-23-35(39,40)41/h2-5,7-10,20-21,24,45H,6,11-19,22-23H2,1H3,(H2,42,46)
• InChI key: InChIKey=NCFJJNFEEPMRAQ-UHFFFAOYSA-N
• SMILES: CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)N(CCOc1ccccc1OCC(F)(F)F)CCOc1ccccc1OCC(F)(F)F