6-Trifluoromethyltetralin-1-one

CAS: 62620-71-7

Ref. TR-T790595

Product Information

• Name: 6-Trifluoromethyltetralin-1-one
• Synonyms: 6-(trifluoromethyl)-3,4-dihydro-2H-naphthalen-1-one, 6-(Trifluoromethyl)-1-tetralone

Description

Applications 6-Trifluoromethyltetralin-1-one is derived from 4-Bromobenzotrifluoride (B680525), which is an aromatic compound that is used as a reagent to synthesize Bergenin (B318650), a compound that originates in Mallotus japonicus that exhibits hepatoprotective and antioxidant effects. 4-Bromobenzotrifluoride is also used as a reagent to prepare (±)-Preclamol, a partial dopamine D2 agonist that is used to treat Parkinson’s disease.
References Lim, H., et al.: Pharmacology, 63, 71 (2001); Parkan, K., et al.: Chem. Eur. J., 20, 4414 (2014); Pirtosek, Z., et al.: Clin. Neuro., 16, 550 (1993); Takahashi, H., et al.: Bioorg. Med. Chem., 11, 1781 (2003); Vasdev, N., et al.: Synapse, 60, 314 (2006)

• Brand: TRC

Chemical properties

• Molecular weight: 214.184
• Formula: C₁₁H₉F₃O
• Color/Form: Neat
• InChI: InChI=1S/C11H9F3O/c12-11(13,14)8-4-5-9-7(6-8)2-1-3-10(9)15/h4-6H,1-3H2
• InChI key: InChIKey=UHPCUZXSDJQOPS-UHFFFAOYSA-N
• SMILES: O=C1CCCc2cc(C(F)(F)F)ccc21