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4-(Trifluoromethoxy)aniline
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4-(Trifluoromethoxy)aniline

CAS: 461-82-5

Ref. TR-T790700

50g
233.00 €
100g
324.00 €
250g
608.00 €
Estimated delivery in United States, on Tuesday 28 Jan 2025

Product Information

Name:
4-(Trifluoromethoxy)aniline
Controlled Product
Synonyms:
  • 4-(Trifluoromethoxy)-benzenamine
  • (4-(Trifluoromethoxy)phenyl)amine
  • 1-Amino-4-(trifluoromethoxy)benzene
  • 4-(Trifluoromethoxy)benzenamine
  • 4-Trifluoromethoxybenzeneamine
  • 4-[(Trifluoromethyl)oxy]aniline
  • p-(Trifluoromethoxy)aniline
  • p-Trifluoromethoxyphenylamine
  • p-Anisidine
  • alpha,alpha,alpha-trifluoro- (6CI,7CI,8CI)
  • See more synonyms
  • alpha,alpha,alpha-Trifluoro-p-anisidine
  • Riluzole Related Compound A
  • Benzenamine, 4-(trifluoromethoxy)-
  • p-Aminotrifluoromethoxybenzene
  • p-Anisidine, α,α,α-trifluoro-
  • α,α,α-Trifluoro-p-anisidine
Description:

Stability Hygroscopic
Applications 4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cilibrizzi, A., et al.: J. Med. Chem., 52, 5044 (2009), Verhaeghe, P., et al.: Bioorg. Med. Chem., 17, 4313 (2009), Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994); Piras, S. et al.: Eur. j. Med. Chem., 75, 169 (2014); Vyas, V. et al.: Eur. J. Med. Chem., 82, 385 (2014);

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
177.12
Formula:
C7H6F3NO
Color/Form:
Neat
InChI:
InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
InChI key:
InChIKey=XUJFOSLZQITUOI-UHFFFAOYSA-N
SMILES:
Nc1ccc(OC(F)(F)F)cc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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