3α,6α,7α-Trihydroxy-5β-cholanic Acid

CAS: 547-75-1

Ref. TR-T795105

Product Information

• Name: 3α,6α,7α-Trihydroxy-5β-cholanic Acid
• Synonyms: Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6α,7α)-, 5β-Cholan-24-oic acid, 3α,6α,7α-trihydroxy- (8CI), 5β-Cholanic acid, 3α,6α,7α-trihydroxy- (7CI), (3α,5β,6α,7α)-3,6,7-Trihydroxycholan-24-oic acid, 3α,6α,7α-Trihydroxy-5β-cholan-24-oic acid, 3α,6α,7α-T
• Brand: TRC
• Description: Applications 3α,6α,7α-Trihydroxy-5β-cholanic Acid is one of the bile acids categorizes under muricholic acid, a group of bile acids found in human urine due to its additional hydroxyl groups. The synthesis of 3α,6α,7α-Trihydroxy-5β-cholanic Acid was shown to be promoted due to overexpression of cholesterol 7α-hydroxylase enzyme.References Debray, D., et al.: Gastroenterol., 142, 1581 (2012); Li, T.G., et al.: Hepatol., 53, 996 (2011)

Chemical properties

• Molecular weight: 408.571
• Formula: C₂₄H₄₀O₅
• Color/Form: Neat
• InChI: InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21-,22+,23-,24-/m1/s1