(6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride

CAS: 69056-38-8

Ref. TR-T795613

Product Information

• Name: (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride
• Synonyms: BioMarin T 1401, Biopten, Kuvan, SUN 0588, Sapropterin Dihydrochloride, Shiratori SN 0588
• Brand: TRC
• Description: Stability HygroscopicApplications Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.References Levy, Harvey L., et al.: Lancet, 370, 504 (2007); Isojima, Yasushi., et al.: Proc Natl Acad Sci USA .,106, 15744 (2009); Burton, B. K., et al.: J. Inherit. Metab. Dis., 30, 700 (2007)

Chemical properties

• Molecular weight: 241.25 + 2(36.46)
• Formula: C₉H₁₅N₅O₃·2(HCl)
• Color/Form: White To Off-White
• InChI: InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
• InChI key: InChIKey=RKSUYBCOVNCALL-NTVURLEBSA-N
• SMILES: C[C@H](O)[C@H](O)[C@H]1CNc2[nH]c(=N)[nH]c(=O)c2N1.Cl.Cl