[2-(Trimethylammonium)ethyl]methanethiosulfonate Bromide

CAS: 91774-25-3

Ref. TR-T795900

Product Information

• Name: [2-(Trimethylammonium)ethyl]methanethiosulfonate Bromide
• Synonyms: trimethyl(2-methylsulfonylsulfanylethyl)azanium;bromide, (2-Mercaptoethyl)trimethylammoniumbromide, methanesulfonate (7CI), Ethanaminium, N,N,N-trimethyl-2-[(methylsulfonyl)thio]-,bromide (9CI), 2-(Trimethylammonium)ethyl methanethiosulfonate bromide, Mtset, Methanethiosulfonate ethyltrimethylammonium bromide

Description

Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.
References Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Vedantham, V. and Cannon, C.C.: J. Gen. Physiol., 111, 83 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000), Sullivan, D.A. and cohen, J.B.: J. B.C., 275, 17, 12651 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 278.23
• Formula: C₆H₁₆NO₂S₂·Br
• Color/Form: White To Off-White
• InChI: InChI=1S/C6H16NO2S2.BrH/c1-7(2,3)5-6-10-11(4,8)9;/h5-6H2,1-4H3;1H/q+1;/p-1
• SMILES: C[N+](C)(C)CCSS(C)(=O)=O.[Br]