Product Information
Name:O-Trimethyl GFT-505
Controlled Product
Synonyms:
- (E)-t-Butyl 2-(2,6-Dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoate
Brand:TRC
Description:Applications O-Trimethyl GFT-505 is an intermediate in synthesizing GFT-505 (G368870), which is a dual PPARα/δ agonist. Studies have shown that GFT-505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. It may also be a potential new drug candidate for treating lipid and glucose disorders.References Carious, B., et al.: Diabetes Care 36, 2923 (2013); Carious, B., et al.: Diabetes Care 34, 2008 (2011);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:440.59
Formula:C26H32O4S
Color/Form:Neat
InChI:InChI=1S/C26H32O4S/c1-17-15-19(9-14-22(27)20-10-12-21(31-8)13-11-20)16-18(2)23(17)29-26(6,7)24(28)30-25(3,4)5/h9-16H,1-8H3/b14-9+
InChI key:InChIKey=YYPZICPPNBONPZ-NTEUORMPSA-N
SMILES:CSc1ccc(C(=O)/C=C/c2cc(C)c(OC(C)(C)C(=O)OC(C)(C)C)c(C)c2)cc1
Technical inquiry about: O-Trimethyl GFT-505
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