(3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholan-24-al

Ref. TR-T887895

Product Information

• Name: (3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholan-24-al

Description

Applications (3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholan-24-al is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.
References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 566.81
• Formula: C₃₃H₅₈O₇
• Color/Form: Neat
• InChI: InChI=1S/C33H58O7/c1-7-35-20-38-25-14-15-32(5)24(17-25)18-29(39-21-36-8-2)31-27-13-12-26(23(4)11-10-16-34)33(27,6)30(19-28(31)32)40-22-37-9-3/h16,23-31H,7-15,17-22H2,1-6H3/t23-,24+,25-,26-,27?,28?,29-,30+,31?,32+,33-/m1/s1
• InChI key: InChIKey=FOAAZVLIXQMOHD-BICFILNQSA-N
• SMILES: CCOCO[C@H]1CC2C(C3CC[C@H]([C@H](C)CCC=O)[C@]31C)[C@H](OCOCC)C[C@@H]1C[C@H](OCOCC)CC[C@]21C