Product Information
Name:Vadimezan
Controlled Product
Synonyms:
- 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic Acid
- 5,6-Dimethyl-9-oxo-9H-xanthen-4-ylacetic Acid
- 5,6-Dimethylxanthenone-4-acetic Acid
- AS 1404
- ASA 404
- DMXAA
- NSC 640488
- 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic Acid
Brand:TRC
Description:Applications Vadimezan is a drug that displayed vascular-disrupting activity and induced haemorrhagic necrosis and tumour regression in pre-clinical animal models. It is a substrate for the immune adaptor protein STING in mice.References Buchanan, C.M., et al.: Clin. Sci., 122, 449 (2012); Fruh, M., et la.: Clin. Lung. Cancer., 14, 34 (2013); Chem. and Eng. News page 24 Feb. 26, 2018
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:282.29
Formula:C17H14O4
Color/Form:Neat
InChI:InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
InChI key:InChIKey=XGOYIMQSIKSOBS-UHFFFAOYSA-N
SMILES:Cc1ccc2c(=O)c3cccc(CC(=O)O)c3oc2c1C
Technical inquiry about: Vadimezan
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