δ-Valerolactam-d4

CAS: 675-20-7

Ref. TR-V091441

Product Information

• Name: δ-Valerolactam-d4
• Synonyms: 2-Piperidinone-d4, 2-Piperidone-d4, 2-Oxopiperidine-d4, 5-Pentanolactam-d4, 5-Amino-pentanoic Acid Lactam-d4, Valerolactim-d4, a-Piperidone-d4, 2-Oxopiperidine, 2-Piperidinone, 2-Piperidon, 2-Piperidona, 5-Aminopentanoic acid lactam, 5-Pentanolactam, Delta-valerolactam, Nsc 18894, Nsc 2305, Pentanoic acid, 5-amino-, lactam, Piperidin-2-One, Valerolactim, α-Piperidone, δ-Valerolactam

Description

Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.
References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 103.16
• Formula: C₅H₅D₄NO
• Color/Form: Neat
• InChI: InChI=1S/C5H9NO/c7-5-3-1-2-4-6-5/h1-4H2,(H,6,7)/i1D2,2D2
• InChI key: InChIKey=XUWHAWMETYGRKB-LNLMKGTHSA-N
• SMILES: [2H]C1([2H])CNC(=O)CC1([2H])[2H]