D-Valine

CAS: 640-68-6

Ref. TR-V094200

Product Information

• Name: D-Valine
• Synonyms: (-)-2-Amino-3-methylbutyric Acid, (R)-3-Methyl-2-aminobutanoic Acid, (R)-Valine, NSC 20654, (-)-2-Amino-3-methylbutyric acid, (2R)-2-Amino-3-methylbutanoic acid, (R)-2-Amino-3-methylbutanoic acid, (R)-3-Methyl-2-aminobutanoic acid, <span class="text-smallcaps">D</span>-(-)-Valine, D-2-Amino-3-methylbutanoic acid, D-Valin, D-valina, H-D-Val-OH, Nsc 20654, Valine, <span class="text-smallcaps">D</span>-, Valine, D-, D-(-)-Valine

Description

Applications D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.
References Gilbert, S.F. et al.: Cell, 5, 11 (1975); Hongpaisan, J. et al.: Cell Biol. Int., 24, 1 (2000); Sasamura, T. et al.: J, Nutrit. Sci. Vitaminol., 44, 89 (1998);

• Brand: TRC

Chemical properties

• Molecular weight: 117.15
• Formula: C₅H₁₁NO₂
• Color/Form: Neat
• InChI: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
• InChI key: InChIKey=KZSNJWFQEVHDMF-SCSAIBSYSA-N
• SMILES: CC(C)[C@@H](N)C(=O)O