L-Valine Methyl Ester Hydrochloride

CAS: 6306-52-1

Ref. TR-V094325

Product Information

• Name: L-Valine Methyl Ester Hydrochloride
• Synonyms: L-Valine, methyl ester, hydrochloride (1:1), L-Valine, methyl ester, hydrochloride (9CI), Valine, methyl ester, hydrochloride, L- (6CI,7CI,8CI), (S)-Valine methyl ester hydrochloride, Methyl (S)-2-amino-3-methylbutanoate hydrochloride, Methyl (S)-valinate hydrochloride, Methyl L-valinate hydrochloride, Methyl valinate hydrochloride, NSC 197198, NSC 22920, Valine methyl ester hydrochloride, <span class="text-smallcaps">L</span>-Valine, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-Valine, methyl ester, hydrochloride (1:1), L-Valine, methyl ester, hydrochloride (1:1), Methyl <span class="text-smallcaps">L</span>-valinate hydrochloride, Methyl <span class="text-smallcaps">L</span>-valine hydrochloride, Methyl Valinate Hydrochloride, Methylvalinathydrochlorid, Nsc 197198, Nsc 22920, Valinate De Methyle, Chlorhydrate, Valinato De Metilo, Clorhidrato, Valine, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-, Valine, methyl ester, hydrochloride, L-, Val-ome.hcl, H-Val-OMe.HCl, L-Valine, methyl ester, hydrochloride, L-Valine methyl ester HCL, methyl L-valinate, (2R)-1-methoxy-3-methyl-1-oxobutan-2-aminium, L-Valine Methyl Estet HCL, (S)-Methyl 2-amino-3-methylbutanoate hydrochloride, H-Val-OMe・HCl, (2S)-1-methoxy-3-methyl-1-oxobutan-2-aminium, H-Val-OMe• HCl

Description

Applications L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
References McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 167.63
• Formula: C₆H₁₃NO₂·ClH
• Color/Form: Neat
• InChI: 1H/t5-, /h4-5H,7H2,1-3H3, /m0./s1, InChI=1S/C6H13NO2.ClH/c1-4(2)5(7)6(8)9-3