L-Valinol

CAS: 2026-48-4

Ref. TR-V094340

Product Information

• Name: L-Valinol
• Synonyms: L-2-Amino-3-methyl-1-butanol, (+)-(S)-Valinol, (+)-2-Amino-3-methyl-1-butanol, (+)-Valinol, (2S)-1-Hydroxy-3-methylbutan-2-amine, (2S)-2-Amino-3-methyl-1-butanol, (2S)-Valinol, (S)-(+)-2-Amino-3-methyl-1-butanol, (S)-(+)-Valinol, (S)-2-Amino-3-methyl-1-butanol, (S)-2-Amino-3-methylbutanol, (S)-Valinol, NSC 322922, [(S)-1-(Hydroxymethyl)-2-methylpropyl]amine, 1-Butanol, 2-amino-3-methyl-, (S)-, 1-Butanol, 2-amino-3-methyl-, <span class="text-smallcaps">L</span>-, 1-Butanol, 2-amino-3-methyl-, L-, <span class="text-smallcaps">L</span>-Valinol, Butanol, 2-Amino-3-Methyl, (S)-(+)-, L-2-amino-3-methylbutan-1-ol, L-2-amino-3-methylbutane-1-ol, L-2-amino-3-metilbutan-1-ol, Nsc 322922

Description

Applications L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.
References Chen, N., et al.: Phosphorus Sulfur, 190, 112 (2015); Zhao, Y., et al.: J. Med. Chem., 58, 1038 (2015)

• Brand: TRC

Chemical properties

• Molecular weight: 103.163
• Formula: C₅H₁₃NO
• Color/Form: White
• InChI: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m1/s1