Valinomycin

CAS: 2001-95-8

Ref. TR-V094370

Product Information

• Name: Valinomycin
• Synonyms: (3S,6S,12R,15S,18S,21R,24R,27S,30S,33R,36R)-6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nona(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone, 1,7,13,19,25,31-Hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone, 3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-, Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl), Nsc 122023, Valinomicin, Valinomicina, Valinomycine

Description

Applications K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. Used as insecticide, nematocide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ivanov, et al.: Biochem. Biophys. Res. Commun., 34, 803 (1969), Duax, et al.: Science, 176, 911 (1972),

• Brand: TRC

Chemical properties

• Molecular weight: 1111.32
• Formula: C₅₄H₉₀N₆O₁₈
• Color/Form: Neat
• InChI: InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36?,37-,38-,39-,40+,41+,42+/m0/s1
• InChI key: InChIKey=FCFNRCROJUBPLU-ZNYTZFDZSA-N
• SMILES: CC1OC(=O)C(C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)NC(=O)C(C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)C(C(C)C)NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)C(C(C)C)OC(=O)C(C(C)C)NC1=O