ent-Valsartan

CAS: 137862-87-4

Ref. TR-V095755

Product Information

• Name: ent-Valsartan
• Synonyms: Valsartan Imp. A (EP), Valsartan USP Related Compound A, Valsartan USP RC A, (2R)-3-Methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic Acid, CGP 49309, D-Valsartan, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-Valine, Valsartan Related Compound A (USP), Valsartan Imp A (EP), Valsartan Related Compound A, Valsartan Impurity A, 3-Methyl-2-[Pentanoyl-[[4-[2-(2H-Tetrazol-5-Yl)Phenyl]Phenyl]Methyl]Amino]-Butanoic Acid, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine, D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, Valsartan(Diovan), N-(1-Oxopentyl)-N-((2'-(1H-Tetrazol-5-Yl)(1,1'-Biphenyl)-3-Yl)Methyl)-L-Valine

Description

Impurity Valsartan USP Related Compound A
Applications ent-Valsartan (Valsartan USP Related Compound A) is the (R)-enantiomer of Valsartan (V095750).
References Corea, L., et al.: Clin. Pharmacol. Ther., 60, 341 (1996), Satana, E;., et al.: J. Pharm. Biomed. Anal., 25, 1009 (2001), Sironi, L., et al.: Hypertension, 37, 961 (2001),

• Brand: TRC

Chemical properties

• Molecular weight: 435.52
• Formula: C₂₄H₂₉N₅O₃
• Color/Form: White
• InChI: InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1
• InChI key: InChIKey=ACWBQPMHZXGDFX-JOCHJYFZSA-N
• SMILES: CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@@H](C(=O)O)C(C)C