Product Information
Name:Verazide
Controlled Product
Synonyms:
- [(3,4-Dimethoxyphenyl)methylene]hydrazide 4-Pyridinecarboxylic Acid
- Veratrylidenehydrazide Isonicotinic Acid
- 1-Isonicotinoyl-2-veratrylidenehydrazine
- 3,4-Dimethoxybenzaldehyde Isonicotinoylhydrazone
- NSC 180261
- Nicotazide
- N'-Veratrylideneisoniazid
- Veratraldehyde Isonicotinoylhydrazone
- Verazina
- 2-[(3,4-Dimethoxyphenyl)methylene]hydrazide
- 4-Pyridinecarboxylic Acid
Brand:TRC
Description:Applications Verazide is derived from Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).References Brewer, G.A., et al.: Anal. Profiles Drug Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:285.298
Formula:C15H15N3O3
Color/Form:Neat
InChI:InChI=1S/C15H15N3O3/c1-20-13-4-3-11(9-14(13)21-2)10-17-18-15(19)12-5-7-16-8-6-12/h3-10H,1-2H3,(H,18,19)/b17-10+
InChI key:InChIKey=HPXIKMBHOXLFOR-LICLKQGHSA-N
SMILES:COc1ccc(/C=N/NC(=O)c2ccncc2)cc1OC
Technical inquiry about: Verazide
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