Product Information
Name:XAV 939
Controlled Product
Synonyms:
- NVP-XAV 939
Brand:TRC
Description:Applications A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Huang, S. et al.: Nature, 461, 614 (2009); Wang, H. et al.: ACS Chem. Biol., 6, 192 (2011); Adles, M.E. et al.: Sci. Signal., 91, ec326 (2009);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:312.31
Formula:C14H11F3N2OS
Color/Form:Neat
InChI:InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChI key:InChIKey=KLGQSVMIPOVQAX-UHFFFAOYSA-N
SMILES:O=c1nc(-c2ccc(C(F)(F)F)cc2)[nH]c2c1CSCC2
Technical inquiry about: XAV 939
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