Zinquin Ethyl Ester

CAS: 181530-09-6

Ref. TR-Z450000

Product Information

• Name: Zinquin Ethyl Ester
• Synonyms: ethyl 2-[2-methyl-8-[(4-methylphenyl)sulfonylamino]quinolin-6-yl]oxyacetate

Description

Applications A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zinc ion with two nitrogen atoms in the structure. Used for studying the role of zinc in apoptosis.Fluorescence: max. Abs. l = 368nm, max. Em. l = 490nm
References Zalewski, P.D., et al.: Biochem.J., 296, 403 (1993), Zalewski, P.D., et al.: J. Histochem. Cytochem., 42, 877 (1994), Zalewski, P.D., et al.: Biochem.J., 303, 278 (1994), Zalewski, P.D., et al.: Chemistry & Biology, 1, 153 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 414.47
• Formula: C₂₁H₂₂N₂O₅S
• Color/Form: Neat
• InChI: InChI=1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3
• InChI key: InChIKey=KCASTCXJTDRDFT-UHFFFAOYSA-N
• SMILES: CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2nc(C)ccc2c1